AIPMT-NEET Biology Aspirants, read out the next AIPMT-NEET Biology Study material/ Notes of types of Antibodies important for AIPMT-NEET Biology. Free online notes for AIPMT-NEET.
Antibodies are also called as Immunoglobin(Ig). Antibodies provide humoral immunity or humoral immune response to body. “Humors” means fluid, and antibodies are found in body fluids like blood and lymph so provide humoral immunity.
There are five classes of Antibodies or Immunoglobins found in the body: IgG, IgA, IgM, IgD, IgE.
Note: Learning tip- GAMED
|Immunoglobin||Name||Percentage in body||No. of Units in structure||Function|
|IgG||ɣ (Gamma)||80 – 85 %||Monomer||Most abundant in blood; only antibody which crosses placenta from mother to fetus to provide protection to newborn (also called as maternal antibody); protects against bacteria, virus, toxins|
|IgA||α (Alpha)||10 – 15 %||Monomer or dimer||Called as Secretory antibody as found in body secretions like sweat, tears, saliva, & breast milk. IgA passes from mother to fetus through breast milk during lactation. Colostrum (yellowish fluid) secreted by mother after birth also called as first milk has highest percentage of IgA.|
|IgM||μ (Mu)||5 -10 %||Pentamer||First antibody to be secreted during exposure of body to any foreign particle/antigen|
|IgD||δ (Delta)||Less than 1 (approx 0.2 %)||Monomer||Help in recognition of foreign particle/antigen|
|IgE||ε (Epsilon)||Less than 0.1%||Monomer||IgE is produced during allergic response of body towards certain antigens like dust, pollen etc. IgE is responsible for hypersensitivity. Produced during Hay Fever & Asthma|